A $4.39 2 oz. tube holds 200 applications (so it says, but the way I use it on my big hands I'm thinking it's more like 40-50 applications. Still.) and it's the best thing I've found for my dry skin. It also says an application lasts 24 hours, though I have found it to last about 18-20 hours, but I wash my hands a lot. I have tried nearly everything on the drugstore shelves, including sleeping with a big glob of Aquaphor with my hands in gloves all night. I tried Neutrogena Norwegian Formula Hand Cream at the recommendation of a friend, and she was right - this stuff is the GOAT!