I work and operate my businesses from home/farm. My entire day is all about balance and keep disciplined to get the job done. I've worked for myself since I was in my early 20's so I have always preferred working at home. The times I did have an office I still worked at home. I don't like a lot of distractions. I'm a fierce multi-tasker and can do two things at once.
My biggest struggle is knowing when to shut it off. Too often I'm grabbing my lap top to finish something or look something up. I can afford to have days where I just don't feel like working but I also know I have to make that time up. I also have to work towards delegation because I'm such a control freak I end up doing task others can easily do.

I'm working on this and seem to be getting better.
Something that works well for me is taking frequent breaks to take a walk outside or if its nice out I'll take my work outside. Luckily I get to work doing the things I love so it all works out great.
I rarely wear shoes and when I do it's simple. I wear very little clothing- T-shirts & jeans or I have all these PJ sets and enjoy simple feminine flowing type things. Anything silky or loose fitting. If I don't have workers around I'll wear these flimsy little cami/slip things. I want to be comfortable. I'm often on the phone and brushing a dog.
Like Linus stated I miss interaction but I do make sure to get out a few times a week.