First Synthetic Organ Transplant

[lionpaw]

Well, I think I found a site that might be worth looking at insofar as scaffolding and creating a suitable human liver for transplantation....The site is: www.medpage.com

It appears like they are onto something....The vascular architecture of the liver is very complicated to replicate via biomedical engineering.....The seeding of the scaffold, how many millions of hepatocytes are needed for a successful regeneration, and successful transplantion---simply enormous....

[ScandalAndy]

Originally Posted by lionpaw

Well, I think I found a site that might be worth looking at insofar as scaffolding and creating a suitable human liver for transplantation....The site is: www.medpage.com

It appears like they are onto something....The vascular architecture of the liver is very complicated to replicate via biomedical engineering.....The seeding of the scaffold, how many millions of hepatocytes are needed for a successful regeneration, and successful transplantion---simply enormous....

I think there's something missing from the link. I see the main medpage homepage but am having trouble figuring out where to navigate to for that particular article.

That was something I was curious about too, regenerating organs requiring vascular structure. It's my understanding that the windpipe, being cartilagenous, is largely exempt from the necessity of regular, abundant blood flow. It seems it would be fairly impossible to regenerate an organ requiring erythrocyte pathways to match exactly.

[lionpaw]

Originally Posted by ScandalAndy

I think there's something missing from the link. I see the main medpage homepage but am having trouble figuring out where to navigate to for that particular article.

That was something I was curious about too, regenerating organs requiring vascular structure. It's my understanding that the windpipe, being cartilagenous, is largely exempt from the necessity of regular, abundant blood flow. It seems it would be fairly impossible to regenerate an organ requiring erythrocyte pathways to match exactly.

I want to add more to this discussion, but I have some things to do...I will be back later....Sorry about the link.....